Does AstraZeneca make tamoxifen?

WASHINGTON — The original manufacturer of the breast-cancer drug tamoxifen will stop selling it in June because of declining sales.

What is the original brand of tamoxifen?

Tamoxifen (Brand Names: Nolvadex, Soltamox) Tamoxifen is the oldest and most-prescribed selective estrogen receptor modulator (SERM).

Is there a shortage of tamoxifen?

There have been some really alarming and scary headlines floating around. But the fact is Tamoxifen is still available, there is just less of it. To help everyone get through the temporary shortage, patients may only get 30-days of their prescriptions at a time.

Why is there a shortage of tamoxifen?

According to Health Canada, there’s a national shortage of Tamoxifen due to manufacturing disruptions and increased demand. There is an international shortage of a common cancer drug called Tamoxifen. Heidi Petracek reports.

Does tamoxifen cause dementia?

Patients with breast cancer exhibited a similar risk of developing dementia. Tamoxifen users exhibited a significant 17% lower risk of dementia compared with those not using tamoxifen. Tamoxifen use of 5 years or more significantly decreased the risk of dementia.

Is tamoxifen an immunosuppressive drug?

Taken together, the evidence from human, in vivo and in vitro studies presented here suggests that tamoxifen modulates immune function with differential effects on Th1 and Th2 immunity, which may be mediated through an estrogen-independent mechanism.

Is tamoxifen toxic to the liver?

Introduction. Tamoxifen is a nonsteroidal antiestrogen that is widely used in the treatment and prevention of breast cancer. Long term tamoxifen therapy has been associated with development of fatty liver, steatohepatitis, cirrhosis, and rare instances of clinically apparent acute liver injury.

Can you take vitamin D with tamoxifen?

No interactions were found between tamoxifen and Vitamin D3.

What is the alternative to tamoxifen?

Earlier ATAC results found that Arimidex was more effective than tamoxifen in reducing the risk of recurrence of early-stage, hormone-receptor-positive breast cancer in postmenopausal women. Other studies comparing tamoxifen to the other two aromatase inhibitors (Aromasin and Femara) have shown similar results.

What does tamoxifen do to the body?

Tamoxifen is a type of hormonal therapy known as a selective estrogen receptor modulator (SERM). The drug attaches to hormone receptors (specific proteins) in breast cancer cells. Once the medication is inside the cells, it stops the cancer from accessing the hormones they need to multiply and grow.

Who is the manufacturer of tamoxifen in the UK?

Tamoxifen was developed by UK-based Imperial Chemical Industries (ICI), one of the world’s largest multinational chemical corporations. Zeneca, an ICI subsidiary, is responsible for manufacturing and marketing the hormone and is now the world’s largest cancer-drug company.

Is there a generic version of tamoxifen available?

The generic Tamoxifen is manufactured by one company. Medindia’s drug directory has currently 28 Brands of Tamoxifen listed. New generics and brands are constantly being updated as and when they are approved by drug controller and available in the pharmacies. Tamoxifen (Nolvadex) generic is an antiestrogen, prescribed for breast cancer.

What kind of cancer does tamoxifen systemic treat?

tamoxifen systemic. Brand names: Nolvadex, Tamoxen, Tamosin, Soltamox. Drug class(es): hormones/antineoplastics, selective estrogen receptor modulators. Tamoxifen systemic is used in the treatment of: Breast Cancer. Breast Cancer, Adjuvant. Breast Cancer, Male. Breast Cancer, Metastatic.

Where can I get a tamoxifen citrate tablet?

Tamoxifen Citrate tablets are only sold in the US. For further information, please contact US Customer Service at +1 800 344 8661. To report SUSPECTED ADVERSE REACTIONS, contact Mayne Pharma at 1-844-825-8500 or FDA at 1 800-FDA-1088 or